Berberine Analogues as a Novel Class of the Low-Density-Lipoprotein Receptor Up-Regulators: Synthesis, Structure−Activity Relationships, and Cholesterol-Lowering Efficacy
Author:
Affiliation:
1. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China, and National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm801157z
Reference20 articles.
1. Relationship of Baseline Serum Cholesterol Levels in 3 Large Cohorts of Younger Men to Long-term Coronary, Cardiovascular, and All-Cause Mortality and to Longevity
2. Cholesterol and Mortality
3. Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
4. Human low-density lipoprotein receptor gene and its regulation
5. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
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