Development of a Practical and Scalable Synthetic Route to YM758 Monophosphate, A Novel If Channel Inhibitor-Reference-Cited by-同舟云学术

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Development of a Practical and Scalable Synthetic Route to YM758 Monophosphate, A Novel If Channel Inhibitor

Published:2014-11-03 Issue:12 Volume:18 Page:1721-1727
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Yoshida Shinya¹,Marumo Kiyotaka²,Takeguchi Kazuhiro¹,Takahashi Takumi³,Mase Toshiyasu¹

Affiliation:

1. Process Chemistry Labs., Astellas Pharma Inc., 160-2 Akahama, Takahagi-shi, Ibaraki 318-0001, Japan

2. Astellas Pharma Tech Co., Ltd., 160-2 Akahama, Takahagi-shi, Ibaraki 318-0001, Japan

3. Technology Product Management, Astellas Pharma Inc., 2-5-1, Nihonbashi-Honcho, Chuo-ku, Tokyo, 103-8411, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op5002885

Reference20 articles.

1. Synthesis and Pharmacological Evaluation of 2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinoline Derivatives as Specific Bradycardic Agents.

2. AN EFFICIENT SYNTHESIS OF (±)-6,7-DIMETHOXY-1-OXO-2-(3-PIPERIDYL)-1,2,3,4-TETRAHYDROISOQUINOLINE

3. eWatanabe, T.; Kakefuda, A.; Masuda, N.WO9813364, 1998.

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