Stereoselective Oxidation of Aryl-Substituted Vicinal Diols into Chiral α-Hydroxy Aldehydes by Re-Engineered Propanediol Oxidoreductase
Author:
Affiliation:
1. Department of Chemistry−BMC, Uppsala University, Box 576, SE-751 23 Uppsala, Sweden
2. Structural Bioinformatics Laboratory, Åbo Akademi University, Tykistökatu 6A, FIN-20520 Turku, Finland
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/cs400824h
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4. Biocatalytic Strategies for the Asymmetric Synthesis of α-Hydroxy Ketones
5. Asymmetric syntheses based on 1,3-oxathianes. 2. Synthesis of chiral tertiary .alpha.-hydroxy aldehydes, .alpha.-hydroxy acids, glycols [R1R2C(OH)CH2OH], and carbinols [R1R2C(OH)Me] in high enantiomeric purity.
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