High-Affinity Inhibitors of Dihydrofolate Reductase: Antimicrobial and Anticancer Activities of 7,8-Dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with Small Molecular Size
Author:
Affiliation:
1. Wellcome Research Laboratories, Research Triangle Park, North Carolina 27709, Wellcome Research Laboratories, Beckenham, Kent BR3 3BS, U.K., and Duke University Medical Center, Durham, North Carolina 27710
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm9505122
Reference78 articles.
1. Dihydrofolate reductase as a therapeutic target
2. Karnofsky memorial lecture. Ode to methotrexate.
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