Characterization of Cardiac Glycoside Natural Products as Potent Inhibitors of DNA Double-Strand Break Repair by a Whole-Cell Double Immunofluorescence Assay-Reference-Cited by-同舟云学术

Characterization of Cardiac Glycoside Natural Products as Potent Inhibitors of DNA Double-Strand Break Repair by a Whole-Cell Double Immunofluorescence Assay

Published:2016-03-09 Issue:11 Volume:138 Page:3844-3855
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Surovtseva Yulia V.¹,Jairam Vikram²,Salem Ahmed F.²,Sundaram Ranjini K.²,Bindra Ranjit S.²,Herzon Seth B.³⁴

Affiliation:

1. Yale Center for Molecular Discovery, West Haven, Connecticut 06516, United States

2. Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06511, United States

3. Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States

4. Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut 06511, United States

Funder

CureSearch for Children's Cancer

National Institutes of Health

Yale Center for Molecular Discovery

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.6b00162

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4. The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

5. Mechanism of homologous recombination: mediators and helicases take on regulatory functions

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