Evidence-based treatments of addiction

Author:

O'Brien Charles P1

Affiliation:

1. Department of Psychiatry, University of Pennsylvania3900 Chestnut Street, Philadelphia, PA 19104-6178, USA

Abstract

Both pharmacotherapy and behavioural treatment are required to relieve the symptoms of addictive disorders. This paper reviews the evidence for the benefits of pharmacotherapy and discusses mechanisms where possible. Animal models of addiction have led to some medications that are effective in reducing symptoms and improving function but they do not produce a cure. Addiction is a chronic disease that tends to recur when treatment is stopped; thus, long-term treatment is recommended.

Publisher

The Royal Society

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

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