X-ray phase imaging: from synchrotron to hospital

Author:

Momose Atsushi1,Yashiro Wataru1,Kido Kazuhiro2,Kiyohara Junko2,Makifuchi Chiho2,Ito Tsukasa2,Nagatsuka Sumiya2,Honda Chika2,Noda Daiji3,Hattori Tadashi3,Endo Tokiko4,Nagashima Masabumi5,Tanaka Junji6

Affiliation:

1. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan

2. KonicaMinolta Medical and Graphic, Inc., 2970 Ishikawa-machi, Hachioji, Tokyo 192-8505, Japan

3. Laboratory of Advanced Science and Technology for Industry, University of Hyogo, 3-1-2 Kouto, Kamigori, Hyogo 678-1205, Japan

4. Nagoya Medical Center, 4-1-1 Sannomaru, Naka-ku, Nagoya, Aichi 460-0001, Japan

5. Department of Anatomy, Saitama Medical University, 38 Morohongo, Moroyama, Iruma, Saitama 350-0495, Japan

6. Department of Radiology, Saitama Medical University, 38 Morohongo, Moroyama, Iruma, Saitama 350-0495, Japan

Abstract

With the aim of clinical applications of X-ray phase imaging based on Talbot–Lau-type grating interferometry to joint diseases and breast cancer, machines employing a conventional X-ray generator have been developed and installed in hospitals. The machine operation especially for diagnosing rheumatoid arthritis is described, which relies on the fact that cartilage in finger joints can be depicted with a dose of several milligray. The palm of a volunteer observed with 19 s exposure (total scan time: 32 s) is reported with a depicted cartilage feature in joints. This machine is now dedicated for clinical research with patients.

Publisher

The Royal Society

Subject

General Physics and Astronomy,General Engineering,General Mathematics

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