Sodium Hyaluronate Combined with Jintiange on Knee Joint Function After Arthroscopy for Knee Osteoarthritis

Abstract

Objective: To explore the effects of sodium hyaluronate combined with Jintiange on knee joint function after arthroscopic debridement. Methods: Totally 122 knee osteoarthritis patients underwent arthroscopic debridement were randomized into control and experimental groups. The interleukin-1β, interleukin-6 and tumor necrosis factor-α serum levels were tested via Elisa before and after treatment. The Lysholm knee joint function score, effective rate of treatment, interleukin-1β, interleukin-6 and tumor necrosis factor-α expression, visual analogue scale of pain, incidence of adverse reactions and patient satisfaction were compared. Results: Compared with the control group, the effective rate of treatment and the score of Lysholm knee joint function in the other were higher (both P <0.001), and the serum interleukin-1β, interleukin-6, tumor necrosis factor-α expression and visual analogue scale score were lower (all P <0.001). The incidence of adverse reactions revealed no marked difference (P >0.05), but the satisfaction scores of the experimental group were higher (P <0.01). Conclusion: sodium hyaluronate combined with Jintiange is helpful for knee joint function recovery after arthroscopic knee osteoarthritis, which effectively decreases the level of inflammatory factors and increase patients’ satisfaction.