A Preliminary Study on the Correlation Between TILs and CTCs and Clinical Value in Lung Cancer Patients Analyzed by Lipid Magnetic Microspheres-Reference-Cited by-同舟云学术

A Preliminary Study on the Correlation Between TILs and CTCs and Clinical Value in Lung Cancer Patients Analyzed by Lipid Magnetic Microspheres

Published:2024-11-01 Issue:11 Volume:16 Page:1167-1176
ISSN:1947-2935
Container-title:Science of Advanced Materials
language:en
Short-container-title:sci adv mater

Author:

Liu Rongxing¹,Shen Qiurong¹,Lu Hongjun¹,Wu Zhihua¹

Affiliation:

1. Department of Thoracic Surgery, The Second Hospital of Longyan, Longyan City, Fujian Province, China

Abstract

The purpose of this study was to analyze the advantages of TCR gene and its relationship with tumor infiltrating lymphocytes (til) and circulating tumor cells (CTCs). The properties of EpCAM and EGFR lipid magnetic microspheres were analyzed. The levels of Programmed cell death 1 ligand 1, B7-H3 and B7-H4 in peripheral blood were measured by quantitative immunofluorescence (QIF). T cell receptor expression profile and clone proliferation were detected. The prepared EpCAM and EGFR lipid magnetic microspheres showed good stability and specificity. The therapeutic method proposed in this study is expected to be applied.

Publisher

American Scientific Publishers

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