Computed Tomography-Guided Biopsy Assisted by 18F-FDG Coincidence Imaging for Solid Tumours

Abstract

Objective: Early diagnosis of solid tumour is the key to making treatment plans. The traditional computed tomography (CT)-guided percutaneous biopsy often makes it difficult to determine the puncture point. The aim of this study is to analyze the collaborative application value of CT-guided biopsy assisted by 18F-FDG coincidence imaging for solid tumours. Methods: A retrospective analysis of 15 patients who underwent routine radiological examination can not form a correct diagnosis on body solid tumour. The needle was introduced under CT guidance in a step-by-step technique and correct needle position in the centre of FDG high concentration area in coincidence imaging. The biopsy specimens were examined under light microscopy and immunofluorescence. Result: All the lesions were successfully punctured, and the final diagnosis was malignant in 14 cases and benign in 1 cases. The sensitivity of CT-guided biopsy assisted by coincidence imaging was 92.9% (13/14), and the specificity was 100% (1/1). Compared with clinical final diagnosis, there was no significant difference between the two groups (P >0.05). Two cases of lung biopsy patients had a small amount of blood in sputum after operation. Conclusion: The CT-guided biopsy assisted by 18F-FDG coincidence imaging may improve the diagnostic capability, especially in cases when a definitive diagnosis by imaging alone is difficult to make.