Efficacy of Nano-Silver Dressing Combined with Silver Sulfadiazine Cream in the Treatment of Second-Degree Burn Wounds

Abstract

This study investigates the clinical efficacy of nanosilver dressing combined with silver sulfadiazine cream (SSC) in the treatment of second-degree burn wounds. A total of 100 patients with second-degree burns admitted to our hospital from January 2022 to March 2023 were selected. The patients were randomly divided into a control group (n = 50) and an observation group (n = 50). The control group used SSC, while the observation group used nanosilver dressings based on the control group. The incidence of complications, clinical efficacy, wound healing rate, bacterial culture positive rate, pigmentation clearance time, and inflammatory factor levels before and after treatment were analyzed in the two groups. We observed a significantly higher total effective rate in the observation group (97%) compared to the control group (88%). The incidence of complications was significantly lower in the observation group (10%) than in the control group (64%). Additionally, we found that the wound healing rate was higher and wound healing time was shorter in the observation group compared to the control group. The pigmentation clearance time was significantly shorter in the observation group. After treatment, the levels of inflammatory factors TNF-α, IL-6, and CRP were significantly lower in the observation group compared to those in the control group. Moreover, we observed a significantly lower bacterial culture positive rate and pain intensity in the observation group compared to the control group. Overall, this combined application provides a safe and effective option for treating second-degree burn wounds.