Affiliation:
1. M.V. Lomonosov Moscow State University
Abstract
A novel approach to 2-(1-arylalkyl)benzoxazoles via a reaction of arylboronic acids with 2-(5-iodo-1,2,3-triazolyl)phenols has been developed. The key intermediates of the proposed cascade transformation are 2-(1-diazoalkyl)benzoxazoles, entering reductive C-C-coupling with boronic acids. The reaction proceeds under transition-metal-free conditions and affords target compounds in yields up to 67%.
Publisher
The Russian Academy of Sciences