Addition of alcohols to 4-methylene-1,3-dioxolanes

Abstract

The addition of alcohols to 2-methylene-1,4-dioxaspiro[4.5]decane under the conditions of CF3CO2H catalysis occurs with the selective formation of the corresponding alkoxy derivatives. The conditions that ensure the preparative isolation of target compounds in 63-94% yields are determined, and the relative activity of alcohols in the addition reaction at the exocyclic double bond of substrates is determined.