Fibrin- and Fibrinogenolytic Effect of Extracellular Proteinases of Microfungi Aspergillus alliaceus 7dN1 and A. terreus 2-Reference-Cited by-同舟云学术

Fibrin- and Fibrinogenolytic Effect of Extracellular Proteinases of Microfungi Aspergillus alliaceus 7dN1 and A. terreus 2

Published:2023-07-01 Issue:4 Volume:57 Page:298-300
ISSN:0026-3648
Container-title:Микология и фитопатология
language:
Short-container-title:Mikologiâ i fitopatologiâ

Author:

Osmolovskiy A. A.¹²,Klyagin S. D.¹,Vashkevich T. V.¹,Kurakov A. V.¹,Kreyer V. G.¹

Affiliation:

1. Faculty of Biology of M.V. Lomonosov Moscow State University

2. Faculty of Biotechnology of M.V. Lomonosov Moscow State University

Abstract

Proteolytic cleavage of fibrin and fibrinogen under the action of proteases of microfungi Aspergillus alliaceus 7dN1 and A. terreus 2 was carried out. It was shown that both enzymes can have strong α-fibrinogenase and moderate β-fibrinogenase activity, practically without affecting the γ-chains of these molecules. The products of cleavage in the time interval up to 60 min are polypeptides with a molecular weight of 15 kDa or less.

Publisher

The Russian Academy of Sciences

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