Gold and Silver Compounds as Potential Antitumor Drugs

Author:

Ostrovskaya L. A1,Korman D. B1,Nekrasova E. I1,Chigasova A. K1,Bluhterova N. V1,Rikova V. A1,Fomina Fomina M1,Khochenkova Yu. A2,Abzaeva K. A3

Affiliation:

1. N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences

2. N.N. Blokhin National Medical Research Center for Oncology, Ministry of Health of the Russian Federation

3. V.V. Voevodsky Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences

Abstract

The article presents the generalized results from studies on antitumor activity, cytotoxic effects and mechanisms of action of gold (aurumacryl) and silver (argacryl) polyacrylates in the context of modern ideas about perspectives on the possible use of gold and silver-containing compounds as potential antitumor drugs that showed promising results in experimental studies.

Publisher

The Russian Academy of Sciences

Reference42 articles.

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4. Potential impact of the antirheumatic agent auranofin on proviral HIV-1 DNA in individuals under intensified antiretroviral therapy: Results from a randomised clinical trial

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