On the possibility of non-invasive study of the peripheral mechanisms of autonomous regulation of the human cardiovascular system

Author:

Nesterov V. P1,Burdygin A. I1,Ivanov K. B1,Korotkov S. M1,Sobol K. V1,Soroko S. I1,Shemarova I. V1

Affiliation:

1. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences

Abstract

The aim of this study was to evaluate the possibility of using the developed method of arterial piezopulsometry for non-invasive study of peculiarities of the functioning of peripheral mechanisms of autonomic regulation of the cardiovascular system in patients of different age and health state. Study emphasizes the importance of determining the variability of the parameters of blood pressure pulse waves as a measure of assessing the participation and role of the components of the neuroendocrine (sympatho-adrenal) efferent link in the formation of a fast and well-regulated response of systemic hemodynamics, using myocytes of the left ventricle of the heart as effectors. This paper discusses the possibility and expediency of personalized use of the arterial piezopulsometry method for pulsometric diagnostics of the functional state and nature of autonomic regulation of the functions of cardiovascular system in patients in order to be able to detect earlier pathological conditions and disorders of peripheral mechanisms that ensure adequate blood supply in humans.

Publisher

The Russian Academy of Sciences

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