External-beam neutron therapy: the first domestic medical unit

Author:

Mardynsky Yu. S.1,Gulidov I. A.1,Gordon K. B.12,Кoryakin S. N.13,Solovyov А. N.13,Saburov V. О.1,Ivanov S. A.12,Kaprin А. D.24,Lobzhanidze Т. K.5,Маrkov N. V.5,Zheleznov I. М.6,Yurkov D. I.67,Gerasimchuk О. A.67,Presnyakov А. Y.6,Zverev V. I.67,Smirnov V. P.5

Affiliation:

1. A. Tsyb Medical Radiological Research Center, Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation

2. Lumumba Peoples’ Friendship University of Russia

3. Obninsk Institute of nuclear energy энергетики – branch of the National Research Nuclear University “MEPHI”

4. National Medical Research Radiological Center of the Ministry of Health of the Russian Federation

5. Research Institute of technical physics and automatization

6. Dukhov Automatics Research Institute (VNIIA)

7. National Research Nuclear University “MEPHI”

Abstract

Modern radiotherapy, employing traditional linear accelerators, has nearly reached its apex in terms of efficacy in treating oncological diseases. The challenge before researchers in the field of implementing cutting-edge technologies pertains to the utilization of fundamentally different therapeutic approaches, one of which is remote neutron therapy. Its salient advantages include an increased relative biological effectiveness of radiation, while the complexities of implementing specific technological solutions encompass forming a beam of the required geometry and spectral characteristics. The article delineates the key milestones in the development of the usage of fast neutron beams for remote radiotherapy, a general description of the neutron therapy complex and its primary structural components is also presented. These are currently being developed as an innovative, mass-producible medical project.

Publisher

The Russian Academy of Sciences

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