Spatial and temporal measurements of temperature and cell viability in response to nanoparticle-mediated photothermal therapy-Reference-Cited by-同舟云学术

Spatial and temporal measurements of temperature and cell viability in response to nanoparticle-mediated photothermal therapy

Published:2012-11 Issue:11 Volume:7 Page:1729-1742
ISSN:1743-5889
Container-title:Nanomedicine
language:en
Short-container-title:Nanomedicine

Author:

Whitney Jon R¹,Rodgers Amanda²,Harvie Erica³,Carswell William F⁴,Torti Suzy⁵,Puretzky Alex A⁶,Rouleau Christopher M⁶,Geohegan David B⁶,Rylander Christopher G³,Rylander Marissa N³

Affiliation:

1. Department of Mechanical Engineering & School of Biomedical Engineering & Sciences, Virginia Tech, VA 24061, USA; ICTAS 410 ICTAS, Stanger Street (MC 0193) Blacksburg, VA 24061, USA.

2. Department of Industrial Systems & Engineering, Virginia Tech, VA 24061, USA

3. Department of Mechanical Engineering & School of Biomedical Engineering & Sciences, Virginia Tech, VA 24061, USA; ICTAS 410 ICTAS, Stanger Street (MC 0193) Blacksburg, VA 24061, USA

4. Department of Biological Systems Engineering, Virginia Tech, VA 24061, USA

5. Molecular Microbial & Structural Biology, University of Connecticut, Farmington, CT 06030, USA

6. Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6488 USA

Abstract

Aim: Nanoparticle-enhanced photothermal therapy is a promising alternative to tumor resection. However, quantitative measurements of cellular response to these treatments are limited. This article introduces a Bimodal Enhanced Analysis of Spatiotemporal Temperature (BEAST) algorithm to rapidly determine the viability of cancer cells in vitro following photothermal therapy alone or in combination with nanoparticles. Materials & methods: To illustrate the capability of the BEAST viability algorithm, single wall carbon nanohorns were added to renal cancer (RENCA) cells in vitro and time-dependent spatial temperature maps measured with an infrared camera during laser therapy were correlated with post-treatment cell viability distribution maps obtained by cell-staining fluorescent microscopy. Conclusion: The BEAST viability algorithm accurately and rapidly determined the cell viability as a function of time, space and temperature. Original submitted 13 July 2011; Revised submitted 12 March 2012; Published online 20 July 2012

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

Link

https://www.futuremedicine.com/doi/pdf/10.2217/nnm.12.66

Reference45 articles.

1. Cancer photothermal therapy in the near-infrared region by using single-walled carbon nanotubes

2. Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles

3. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance

4. The current and potential role of hyperthermia in radiotherapy

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Applications;Microbolometers;2022

2. Optical – Magnetic probe for evaluating cancer therapy;Coordination Chemistry Reviews;2021-08

3. Advances in Cancer Therapeutics: Conventional Thermal Therapy to Nanotechnology-Based Photothermal Therapy;Pharmaceutics;2021-07-30

4. Collagen/kerateine multi-protein hydrogels as a thermally stable extracellular matrix for 3D in vitro models;International Journal of Hyperthermia;2021-01-01

5. Combining Chemistry and Engineering for Hepatocellular Carcinoma: Nano-Scale and Smaller Therapies;Pharmaceutics;2020-12-20