Chart review of diagnostic methods, baseline characteristics and symptoms for European patients with pancreatic cancer

Author:

Carrato Alfredo1ORCID,Melisi Davide2ORCID,Prager Gerald3,Westphalen Christoph B4,Ferreras Anabel5,D’Esquermes Nathalie5,Taieb Julien6,Mercadé Teresa M7

Affiliation:

1. Ramón y Cajal University Hospital, Medical Oncology Department, IRYCIS, CIBERONIC, Alcala University, Madrid, Spain

2. Digestive Molecular Clinical Oncology Unit, University of Verona, Verona, Italy

3. Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria

4. Department of Medicine III & Comprehensive Cancer Center Munich, University Hospital, LMU Munich, Munich, Germany

5. Genactis, Mougins, France

6. Sorbonne Paris Cité Hôpital Européen Georges Pompidou, Paris, France

7. Vall d’Hebron University Hospital (HUVH) & Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain

Abstract

Aim: To survey European physicians managing patients with metastatic pancreatic ductal adenocarcinoma (PDAC) and understand differences in baseline characteristics, diagnostic methods, symptoms and co-morbidities. Materials & methods: Patient record inclusion criteria were: ≥18 years old, metastatic PDAC diagnosis and completion of first-line treatment between July 2014 and January 2016. Records were grouped by patient age, gender and primary tumor location. Results: Records (n = 2565) were collected from nine countries. Baseline characteristics varied between subgroups. Computed tomography was the most frequently used diagnostic technique. Symptoms at diagnosis included abdominal and/or mid-back pain (72% of patients) and weight loss (61.5%). Co-morbidities varied with patient age. Conclusion: Greater awareness of symptoms, diagnostic methods and co-morbidities present at PDAC diagnosis may support better patient management decisions.

Funder

Servier

Shire

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Reference40 articles.

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5. Pancreatic Adenocarcinoma

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