The prevalence of hepatitis B and C co-infections among people with HIV-1 in Bulgaria: 2010

The prevalence of hepatitis B and C co-infections among people with HIV-1 in Bulgaria: 2010–2015

Published:2019-12 Issue:12 Volume:14 Page:791-798
ISSN:1746-0794
Container-title:Future Virology
language:en
Short-container-title:Future Virology

Author:

Alexiev Ivailo¹^ORCID,Golkocheva-Markova Elitsa²,Kostadinova Asya¹,Dimitrova Reneta¹,Nikolova Lora¹,Gancheva Anna¹,Tenev Tencho²,Elenkov Ivaylo³,Tcherveniakova Tatiana³,Yancheva Nina³,Stoycheva Mariyana⁴,Doychinova Tsetsa⁵,Pekova Lilia⁶,Alexandrova Marina⁷,Timchev Andon³,Strashimirov Dimitar³,Nikolova Maria⁷

Affiliation:

1. National Reference Confirmatory Laboratory of HIV, National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria

2. National Reference Laboratory of Hepatitis, National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria

3. Specialized Hospital for Active Treatment of Infectious and Parasitic Diseases, Sofia, Bulgaria

4. Department of Infectious Diseases, Medical University, Plovdiv, Bulgaria

5. Department of Infectious Diseases, Medical University, Pleven, Bulgaria

6. Clinic of Infectious Diseases, University Hospital, Stara Zagora, Bulgaria

7. National Reference Laboratory of Immunology, National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria

Abstract

Aim: To evaluate hepatitis B virus (HBV) and hepatitis C virus (HCV) among individuals with HIV/AIDS in Bulgaria diagnosed between 2010 and 2015. Materials & methods: A total of 1158 individuals were diagnosed with HIV/AIDS during the study period. Different transmission groups were tested with ELISA and real-time PCR for HBV and HCV markers. Results: Hepatitis B surface antigen and hepatitis C virus antiboby were found in 9.3 and 23.2% of the tested. HBV DNA and HCV RNA has been found in 47.4 and 69.6%. Hepatitis B and C co-infections were predominant in multiple risk behavior groups, including people who inject drugs, men who have sex with men, prisoners and Roma individuals. Conclusion: HIV prevalence in Bulgaria is low but the rates of hepatitis B and C co-infections among these patients fall within the upper range reported in Europe.

Publisher

Future Medicine Ltd

Subject

Virology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fvl-2019-0092

Reference22 articles.

1. National Statistical Institute of Bulgaria (2015). www.nsi.bg/

2. Detailed Molecular Epidemiologic Characterization of HIV-1 Infection in Bulgaria Reveals Broad Diversity and Evolving Phylodynamics

3. HCV transmission in high-risk communities in Bulgaria

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