Neuropsychological tests for predicting cognitive decline in older adults-Reference-Cited by-同舟云学术

Neuropsychological tests for predicting cognitive decline in older adults

Published:2015-06 Issue:3 Volume:5 Page:191-201
ISSN:1758-2024
Container-title:Neurodegenerative Disease Management
language:en
Short-container-title:Neurodegenerative Disease Management

Author:

Baerresen Kimberly M¹²,Miller Karen J¹,Hanson Eric R³,Miller Justin S⁴,Dye Richelin V¹,Hartman Richard E³,Vermeersch David³,Small Gary W¹

Affiliation:

1. Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90095-6980, USA

2. Veteran Affairs Long Beach Healthcare System, Long Beach, CA 90822, USA

3. Department of Psychology, Loma Linda University, Loma Linda, CA 92350, USA

4. Fuller Theological Seminary, Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90095-6980, USA

Abstract

SUMMARY Aim: To determine neuropsychological tests likely to predict cognitive decline. Methods: A sample of nonconverters (n = 106) was compared with those who declined in cognitive status (n = 24). Significant univariate logistic regression prediction models were used to create multivariate logistic regression models to predict decline based on initial neuropsychological testing. Results: Rey–Osterrieth Complex Figure Test (RCFT) Retention predicted conversion to mild cognitive impairment (MCI) while baseline Buschke Delay predicted conversion to Alzheimer's disease (AD). Due to group sample size differences, additional analyses were conducted using a subsample of demographically matched nonconverters. Analyses indicated RCFT Retention predicted conversion to MCI and AD, and Buschke Delay predicted conversion to AD. Conclusion: Results suggest RCFT Retention and Buschke Delay may be useful in predicting cognitive decline.

Publisher

Future Medicine Ltd

Subject

Neurology (clinical)

Link

https://www.futuremedicine.com/doi/pdf/10.2217/nmt.15.7

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