TRUST-II: a global phase II study of taletrectinib in ROS1 -positive non-small-cell lung cancer and other solid tumors

Author:

Nagasaka Misako12ORCID,Ohe Yuichiro3ORCID,Zhou Caicun4,Choi Chang-min5,Yang Nong6ORCID,Liu Geoffrey7,Felip Enriqueta8ORCID,Pérol Maurice9,Besse Benjamin10ORCID,Nieva Jorge11ORCID,Raez Luis12ORCID,Pennell Nathan A13ORCID,Dimou Anastasios14ORCID,Marinis Filippo de15,Ciardiello Fortunato16,Seto Takashi17ORCID,Hu Zheyi18,Pan Max18,Wang Weiqing18,Li Shuanglian18,Ou Sai-Hong I12ORCID

Affiliation:

1. University of California Irvine School of Medicine, Orange, CA, USA

2. Chao Family Comprehensive Cancer Center, Orange, CA, USA

3. Department ofThoracic Oncology,National Cancer Center Hospital, Tokyo, Japan

4. Department of Medical Oncology,Shanghai Pulmonary Hospital,Tongji University School of Medicine, Shanghai, China

5. Department of Pulmonary and Critical Care Medicine,Asan Medical Center,University of Ulsan College of Medicine, Seoul, Republic of Korea

6. Department of Medical Oncology,Hunan Cancer Hospital,Xiangya School of Medicine,Central South University, Changsha, China

7. Department of Medical Oncology and Hematology,Princess Margaret Cancer Centre,University Health Network, Toronto, Canada

8. Vall d’Hebron Institute of Oncology,Vall d’Hebron University Hospital, Barcelona, Spain

9. Department of Medical Oncology,Léon Bérard Cancer Center, Lyon, France

10. Department of Cancer Medicine,Gustave Roussy Cancer Centre, Villejuif, France;Paris-Saclay University, Orsay, France

11. Division of Medical Oncology,Norris Comprehensive Cancer Center,University of Southern California, Los Angeles, CA, USA

12. Thoracic Oncology Program,Memorial Cancer Institute/Memorial Health Care System,Florida Atlantic University, Miami, FL, USA

13. Cleveland Clinic Taussig Cancer Center, Cleveland, OH, USA

14. Department of Oncology,Mayo Clinic, Rochester, MN, USA

15. European Institute of Oncology, IRCCS, Milan, Italy

16. Department of Precision Medicine,Division of Medical Oncology,University of Campania Luigi Vanvitelli, Naples, Italy

17. Precision Medicine Asia (PREMIA) Co. Ltd, Tokyo, Japan

18. AnHeart Therapeutics, NY, USA

Funder

consulting or advisory role

Publisher

Informa UK Limited

Reference14 articles.

1. NCCN Guidelines Insights: Non-Small Cell Lung Cancer, version 2.2021;Ettinger DS;J. Natl,2021

2. Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer

3. Phase II Study of Crizotinib in East Asian Patients With ROS1-Positive Advanced Non–Small-Cell Lung Cancer

4. Patterns of metastatic spread and mechanisms of resistance to crizotinib in ROS1-positive non-small-cell lung cancer;Gainor JF;JCO Precis. Oncol.,2017

5. Lorlatinib in advanced ROS1-positive non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 1–2 trial

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