Seroprevalence of the hepatitis E virus antibodies among blood donors in the Qassim region, Saudi Arabia

Author:

Alhatlani Bader Y1ORCID,Aljabr Waleed A2,Almarzouqi Mohammed S1,Alhatlani Sami M3,Alzunaydi Rayan N3,Alsaykhan Abeer S3,Almaiman Sulaiman H3,Aleid Ahmed A4,Alsughayir Ammar H5,Bishawri Yara E2,Almusallam Abdulrahman A1

Affiliation:

1. Department of Applied Medical Sciences, Unayzah Community College, Qassim University, Unayzah, Saudi Arabia

2. Research Center, King Fahad Medical City, Riyadh, Saudi Arabia

3. Department of Medical Laboratory, Blood Donor Unit, King Saud Hospital, Unayzah, Saudi Arabia

4. Gastroenterology & Department of Hepatology, King Fahad Medical City, Riyadh, Saudi Arabia

5. Transfusion Medicine & Department of Hematopathology, King Fahad Medical City, Riyadh, Saudi Arabia

Abstract

Aim: Hepatitis E virus (HEV) transmission through blood transfusion is a major public health issue worldwide. We aimed to determine the seroprevalence of HEV in blood donors in the Qassim region of Saudi Arabia. Materials & methods: Serum samples (n = 1078) were collected from volunteer blood donors and tested for the presence of anti-HEV IgG and IgM by indirect ELISA. Results: The seroprevalence of anti-HEV IgG among the blood donors was 5.7% overall. Anti-HEV IgG and IgM seropositivity were significantly higher in non-Saudi donors than in Saudi donors (22.1 vs 3 and 7.8 vs 0.2% for anti-HEV IgG and IgM, respectively). Conclusion: The seroprevalence of HEV among blood donors in the Qassim region was lower than previous estimates for other regions of the country and neighboring countries.

Funder

Qassim University

Publisher

Future Medicine Ltd

Subject

Virology

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