Current management of colorectal liver metastases

Author:

Sunderland Geraint J,Dunne Declan FJ1,Jones Robert P1,Malik Hassan Z1,Poston Graeme J1,Fenwick Stephen W1

Affiliation:

1. Liverpool Hepatobiliary Centre, Aintree University Hospitals NHS Foundation Trust, Lower Lane, Liverpool, L9 7AL, UK

Abstract

SUMMARY  Colorectal cancer is common worldwide and is predicted to become more so in the coming years. The liver is the most common site of metastasis and management is increasingly complex. A multidisciplinary team approach to management is essential, and is associated with better outcomes. Patients with irresectable liver metastases can still benefit from the involvement of a liver specialist, as high secondary resection rates can be achieved with combination chemotherapy, incorporating novel biological therapies and liver-directed local and locoregional treatments. The application of an enhanced recovery model to perioperative care, alongside improvements in the assessment of patient fitness for surgery, should help to mitigate the challenges presented by an older population with increased comorbidity undergoing increasingly complex treatment.

Publisher

Future Medicine Ltd

Subject

Gastroenterology,Oncology

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