Developing biological standards for vaccine evaluation

Author:

Page Mark1,Wilkinson Dianna E1,Mattiuzzo Giada1,Efstathiou Stacey1,Minor Philip1

Affiliation:

1. Division of Virology, National Institute for Biological Standards & Control, Blanche Lane, South Mimms, Potters Bar, Herfordshire, EN6 3QG, UK

Abstract

This perspective describes the process of producing biological reference standards, explains why they are needed, who should use them and in what situations. The aim of this perpective is to promote their use at an early stage of vaccine development and to make developers aware of the advantages in doing so.

Publisher

Future Medicine Ltd

Subject

Virology

Reference14 articles.

1. Wilkinson DE, Page M, Almond N Expert committee on biological standardization preliminary report WHO collaborative study to assess the suitability of interim standards for Ebola virus NAT assays. WHO, Geneva, Switzerland (2015).

2. WHO. WHO consultation on commutability of WHO biological reference preparations forin vitrodetection of infectious markers. Geneva, Switzerland, 21–25 October 2013.

3. Reproducibility of Serologic Assays for Influenza Virus A (H5N1)

4. Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle

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