Elucidating the immunological function of the Cryptococcus neoformans capsule-Reference-Cited by-同舟云学术

Elucidating the immunological function of the Cryptococcus neoformans capsule

Published:2013-09 Issue:9 Volume:8 Page:1107-1116
ISSN:1746-0913
Container-title:Future Microbiology
language:en
Short-container-title:Future Microbiology

Author:

Vecchiarelli Anna¹,Pericolini Eva²,Gabrielli Elena²,Kenno Samyr²,Perito Stefano²,Cenci Elio²,Monari Claudia²

Affiliation:

1. Department of Experimental Medicine, Microbiology Section, University of Perugia, Perugia, 06132, Italy.

2. Department of Experimental Medicine, Microbiology Section, University of Perugia, Perugia, 06132, Italy

Abstract

The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent of life-threatening infections in immunocompromised subjects. A unique characteristic of Cryptococcus species is the presence of a polysaccharide capsule, which is essential for virulence and endows Cryptococcus with potent immunoregulatory properties. This review provides an overview of the immunological properties of the principal components of C. neoformans capsule.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fmb.13.84

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