Cardiac events and economic burden among patients with hypertension and treated insomnia in the USA

Author:

Wickwire Emerson M12ORCID,Amari Diana T3,Juday Timothy R4ORCID,Frech Feride H4,Gor Deval3,Malhotra Manoj4

Affiliation:

1. Department of Psychiatry, University of Maryland, Baltimore, MD 21201, USA

2. Sleep Disorders Center, Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Maryland, Baltimore, MD 21201, USA

3. Genesis Research, Hoboken, NJ 07030, USA

4. Eisai, Inc., Nutley, NJ 07110, USA

Abstract

Background: Cardiovascular (CV) event risk, healthcare resource utilization (HCRU) and costs have not been elucidated among hypertension patients with treated insomnia (H + TI). Materials & methods: Adult patients with H + TI were identified in IBM MarketScan databases. H + TI patients were matched 1:1 on age and sex to controls with hypertension but without sleep disorders. Multivariable models were used to estimate associations between treated insomnia and CV event risk, HCRU and costs. Results: In total, 81,502 H + TI patients (mean age = 62 years, 53% female) were matched. Relative to controls, H + TI patients were 2.4 times as likely to have CV events. H + TI patients incurred higher costs per patient per month (US$2343 vs US$1013). Conclusion: Treated insomnia was associated with higher costs and HRCU in hypertension patients.

Funder

Eisai Inc.

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

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