What do we have that is new in antifungal peptides? A patent review

Author:

Bareño Paula VZ1,Xavier Leonardo C2,Santos Anamaria M3ORCID,Rossato Luana4,da Costa Juliana C5,Serafini Mairim R3ORCID,Novoa Diana MA1,Souto Ricardo B2,Alves Izabel A6ORCID

Affiliation:

1. Department of Pharmacy, National University of Colombia, Bogotá, Colombia

2. Faculty of Pharmacy, Federal University of Bahia, Salvador-BA, Brazil

3. Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil

4. Faculty of Health Sciences, Federal University of Grande Dourados, Dourados-MS, Brazil.

5. Faculty of Pharmacy, Department of Pharmaceutical Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.

6. Postgraduate Program in Pharmaceutical Sciences at the State University of Bahia, Salvador-BA, Brazil & Faculty of Pharmacy, Federal University of Bahia, Salvador-BA, Brazil

Abstract

Drugs used to fight fungal infections may cause toxic or adverse drug interactions. For this reason, there is an increase in the development of natural, semisynthetic and synthetic antifungal peptides. This study aimed to perform a patent review to identify the advances in peptides to treat fungal infections. In a preliminary assessment, 597 patents were identified from the database. Then, duplicated patents (62) and those with titles in disagreement with the scope of this review (196) were excluded. Then, six patents were not in English or Spanish. Following the screening, 288 patents were outside the focus of this review, according to their abstract and description. The final selection covered 45 patents.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

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