Frequency and genotyping of human papillomavirus in patients with DNA tracking technique during 1996-99

Abstract

The prevalence of human papillomavirus (HPV) infections and their role in cervical cancer have been well documented in numerous articles, but it seems that a study in this field in developing countries and the Middle East, including Iran. It's not done. Therefore, the present study was designed and performed to investigate the frequency and genotyping of human papillomavirus in patients by DNA tracking technique. This study was a population-based study in which the frequency and genotyping of human papillomavirus in patients by tracking technique was designed and performed on 534 men and women living in Tehran by DNA tracking technique. Sequences obtained using the NCBI site were analyzed at (http://www.ncbi.nlm.nih.gov/BLAST/LaserGene) and Bio edit software. So that in three low-risk groups including 6 and 11 genotypes, Intermediate risk includes 26-31-33-35-39-40-42-45-49-51-52-53 genotypes -55-56-58-59-66-63-83 and High risk includes 16 and 18 genotypes were divided. According to the results, the prevalence of the papilloma virus in the study population was 21.16%, of which 19.46% were in the high-risk group, 69.89% were in the intermediate-risk group and 50.43% were in the low-risk group. According to the results of the present study, although the prevalence of HPV in the study population is less than in many countries in the world, it is suggested that conducting epidemiological studies in the country to extract the true prevalence and plan to prevent and control this disease.