Primary Hepatic Neuroendocrine Carcinoma: A Rare Entity

Author:

Tidwell Jasmine1,Thakkar Bianca1,Nguyen Minh Thu T.2,Parker Susan3,Schoenfeld Adam4

Affiliation:

1. Department of Medicine, UConn John Dempsey Hospital, Farmington, CT

2. Division of Gastroenterology and Hepatology, Department of Medicine, University of Connecticut, Farmington, CT

3. Department of Pathology and Lab Medicine, Hartford HealthCare, New Britain, CT

4. Division of Gastroenterology and Hepatology, Department of Medicine, Hartford HealthCare, New Britain, CT

Abstract

ABSTRACT Neuroendocrine tumors are typically low-malignancy growths arising from neuroectodermal cells of neural crest origin. Neuroendocrine carcinoma, on the other hand, represents a high-malignancy form of these tumors. While rare in the liver, they often indicate metastasis when present. We present a unique case of incidentally discovered primary hepatic neuroendocrine carcinoma. Initially, the patient's management was based on misleading radiological findings. However, histopathology confirmed the diagnosis, with subsequent imaging ruling out an extrahepatic source. Despite this, the patient opted against surgical intervention, resulting in a fatal outcome. This case underscores the critical importance of prompt diagnosis and intervention to avert adverse outcomes.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference9 articles.

1. Clinical features and outcomes of primary hepatic neuroendocrine carcinomas;Park;J Gastroenterol Hepatol.,2012

2. Primary hepatic neuroendocrine tumor: A case report and literature review;Costa;Int J Surg Case Rep.,2020

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4. Primary hepatic neuroendocrine tumor;Tuan Linh;Endocrinol Diabetes Metab Case Rep.,2021

5. Primary hepatic neuroendocrine tumor: A case report and literature review;Song;World J Clin Cases.,2016

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