Genetic characterization of Brazilian bovine viral diarrhea virus isolates by partial nucleotide sequencing of the 5'-UTR region

Author:

Cortez Adriana1,Heinemann Marcos B2,Castro Alessandra Marnie M.G. de1,Soares Rodrigo M1,Pinto Ana Maria V.3,Alfieri Amauri A.4,Flores Eduardo F.5,Leite Rômulo Cerqueira2,Richtzenhain Leonardo J.1

Affiliation:

1. Universidade de São Paulo, Brazil

2. Universidade Federal de Minas Gerais

3. Universidade Estadual do Norte Fluminense Darcy Ribeiro

4. Universidade Estadual de Londrina

5. Universidade Federal de Santa Maria

Abstract

Nineteen isolates of bovine viral diarrhea virus (BVDV) from Brazil were genetically characterized through partial nucleotide sequencing and analysis of the 5'UTR region. The isolates were grouped as BVDV-1 (11/19), BVDV-2 (6/19) or "atypical" pestivirus (2/19). Among the BVDV-1, eight isolates were classified as subgenotype BVDV-1a, whereas most (4 out of 6) BVDV-2 belonged to subgenotype 2b. Two isolates from aborted fetuses were not classified into any genetic group, being considered atypical BVDVs. Genetic diversity among Brazilian BVDV isolates may be responsible for vaccination and diag-nostic failure and therefore may influence the control strategies for BVDV infection in the country.

Publisher

FapUNIFESP (SciELO)

Subject

General Veterinary

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