Glycemic variability and mortality in oncologic intensive care units

Author:

Oliveira Aretha Pereira de1ORCID,Castro Mariana da Silva2ORCID,Lima Dalmo Valério Machado de1ORCID

Affiliation:

1. Universidade Federal Fluminense, Brazil

2. Universidade Federal do Estado do Rio de Janeiro, Brazil

Abstract

ABSTRACT Objective: This study aimed to investigate the association between glycemic variability and mortality in patients admitted to oncologic intensive care units. Methods: A retrospective cohort study was conducted using a convenience sample of 30 medical records of patients over 18 years of age of both sexes. Glycemic variability was measured using the standard deviation and general amplitude. Statistical analysis was performed using the receiver operating characteristic (ROC) curve and the area under the curve (AUC). The significance level (α) was set at 5% with a confidence interval (CI) of 95%. Results: The study included 14 male patients (46.67%) with a mean age of 60±15 years. A total of 1503 blood glucose samples were collected. The AUC analysis for the standard deviation did not show a statistically significant result (p=.966; 95% CI=[0.283, 0.726]). In contrast, the general amplitude had a statistically significant association with mortality (p=.049; 95% CI=[0.514, 0.916]). Conclusions: This study found that glycemic variability measured by the general amplitude was significantly associated with patient mortality in oncologic intensive care units. These findings suggest that monitoring glycemic variability may be an important factor in the management of critically ill patients in oncologic intensive care units.

Publisher

FapUNIFESP (SciELO)

Subject

General Nursing

Reference31 articles.

1. Admission Hyperglycemia as a Predictor of Mortality in Acute Heart Failure: comparison between the Diabetics and Non-Diabetics;Cho JY;J Clin Med,2020

2. Blood Glucose Levels and Mortality in Patients With Sepsis: Dose-Response Analysis of Observational Studies;Wang W;J Intensive Care Med,2021

3. Mortality rate associated with admission hyperglycemia in traumatic femoral fracture patients is greater than non-diabetic normoglycemic patients but not diabetic normoglycemic patients;Rau CS;Int J Environ Res Public Health,2018

4. The association between hyperglycemia on critical care admission and mortality in critically ill oncology patients;Oliveira A;Can J Crit Care Nurs,2021

5. Intensive insulin therapy in critically ill patients;van den Berghe G;N Engl J Med,2001

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3