Evaluation of recombinant human interferon beta 1b by liquid chromatography methods and bioassay

Author:

Silva Francielle Santos da1,Walter Maurício Elesbão1,Xavier Bruna1,Perobelli Rafaela Ferreira1ORCID,Calegari Guilherme Zanini1,Cardoso Douglas Franco1,Perlin Valquiria Guedes1,Dalmora Sérgio Luiz1ORCID

Affiliation:

1. Federal University of Santa Maria, Brazil

Publisher

FapUNIFESP (SciELO)

Reference25 articles.

1. Immunogenicity of recombinant human interferon beta-1b in immune-tolerant transgenic mice corresponds with the biophysical characteristics of aggregates;Abdolvahab MH;J. Interferon Cytokine Res,2016

2. An albumin-free formulation for escherichia coli-derived interferon beta-1b with decreased immunogenicity in immune tolerant mice;Abdolvahab MH;J Interferon Cytokine Res,2016

3. Characterization and quantitation of aggregates and particles in interferon-β products: potential links between product quality attributes and immunogenicity;Barnard JG;J Pharm Sci,2013

4. Structure-function engineering of interferon-α-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation;Basu A;Bioconjugate Chem,2006

5. Comparative antiproliferative activity in vitro of natural interferons α and β for diploid and transformed human cells;Borden EC;Cancer Res,1982

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