Affiliation:
1. Instituto Nacional de Ciencias Medicas y Nutricion ?Salvador Zubiran?, Mexico
2. Instituto Tecnologico y de Estudios Superiores de Monterrey, Mexico
3. UNAM, Mexico
Abstract
We report on a rare case of an adult with severe hypercalcemia secondary to the ectopic secretion of parathyroid-related peptide (PTH-rP) from a penile squamous cell cancer (PC). A patient of 47 years old was admitted with warty lesions and areas of ulceration covered by purulent material in a large area of the groin, scrotum and penis. Laboratory tests revealed severe hypercalcemia and elevation of PTH-rP; the biopsy reported PC. Hypercalcemia was successfully treated with zoledronic acid, however, the tumor displayed aggressive behavior, which resulted in a poor prognosis for the patient.
Subject
General Medicine,Endocrinology, Diabetes and Metabolism
Reference15 articles.
1. Hypercalcemia of malignancy in hospitalized patients;Jibrin IM;Hospital Physician,2006
2. Cancer-induced hypercalcemia;Lumachi F;Anticancer Res,2009
3. Vitamin D deficiency;Holick MF;N Engl J Med,2007
4. Approach to diagnosis and treatment of hypercalcemia in a patient with malignancy;Reagan P;Am J Kidney Dis,2013
5. Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups;Stewart AF;N Engl J Med,1980
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