Simultaneous circulation of all four dengue serotypes in Manaus, State of Amazonas, Brazil in 2011

Author:

Bastos Michele de Souza1,Figueiredo Regina Maria Pinto de2,Ramasawmy Rajendranath3,Itapirema Evaulino2,Gimaque João Bosco Lima1,Santos Lucilaide Oliveira1,Figueiredo Luiz Tadeu Moraes4,Mourão Maria Paula Gomes5

Affiliation:

1. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado; Universidade do Estado do Amazonas

2. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado

3. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado; Universidade Nilton Lins

4. Faculdade de Medicina de Ribeirão Preto

5. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado; Universidade do Estado do Amazonas; Universidade Nilton Lins

Abstract

INTRODUCTION: Manaus, the capital city of the state of Amazon with nearly 2 million inhabitants, is located in the middle of the Amazon rain forest and has suffered dengue outbreaks since 1998. METHODS: In this study, blood samples were investigated using reverse transcriptase-polymerase chain reaction (RT-PCR), aimed at identifying dengue virus serotypes. RESULTS: Acute phase sera from 432 patients were tested for the presence of dengue virus. Out of the 432 patients, 137 (31.3%) were found to be positive. All the four dengue virus serotypes were observed. CONCLUSIONS: The simultaneous circulation of the four dengue serotypes is described for the first time in Manaus and in Brazil.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,Microbiology (medical),Parasitology

Reference9 articles.

1. Dengue and dengue hemorrhagic fever

2. Dengue and dengue haemorrhagic fever;Gubler DJ.;Clin Microbiol Rev,1998

3. Surto de dengue em Boa Vista Roraima;Osanai CH;Rev Inst Med Trop São Paulo,1983

4. Mem Inst Oswaldo Cruz;Nogueira RMR,1988

5. Exanthematous diseases and the first epidemic of dengue to occur in Manaus, Amazonas, State, Brazil, during 1998-1999;Figueiredo RM;Rev Soc Bras Med Trop,2004

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