The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis-Reference-Cited by-同舟云学术

The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis

Published:2012-05 Issue:3 Volume:107 Page:416-419
ISSN:0074-0276
Container-title:Memórias do Instituto Oswaldo Cruz
language:
Short-container-title:Mem. Inst. Oswaldo Cruz

Author:

Andrade-Neto Valter Viana¹,Matos-Guedes Herbert Leonel de²,Gomes Daniel Cláudio de Oliveira³,Canto-Cavalheiro Marilene Marcuzzo do¹,Rossi-Bergmann Bartira²,Torres-Santos Eduardo Caio¹

Affiliation:

1. Instituto Oswaldo Cruz-Fiocruz, Brasil

2. Universidade Federal do Rio de Janeiro, Brasil

3. Universidade Federal do Rio de Janeiro, Brasil; Universidade Federal do Espírito Santo, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

Microbiology (medical)

Link

http://www.scielo.br/pdf/mioc/v107n3/18.pdf

Reference16 articles.

1. Molecular mechanisms of antimony resistance in Leishmania;Ashutosh SS;J Med Microbiol,2007

2. Effects of ketoconazole on sterol biosynthesis by Leishmania mexicana mexicana amastigotes in murine macrophage tumor cells;Berman JD;Mol Biochem Parasitol,1986

3. Induction of resistance to azole drugs in Trypanosoma cruzi;Buckner FS;Antimicrob Agents Chemother,1998

4. Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica;Coderre JA;Proc Natl Acad Sci USA,1983

5. Characterization of Leishmania (Leishmania) amazonensis promastigotes resistant to pentamidine;Coelho AC;Exp Parasitol,2008

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