The utilization of kallistatin as a novel biomarker for the determining of serum in diagnosing liver diseases of animals

Abstract

Kallistatin is a novel biomarker, a plasma protein produced by the liver, utilized for diagnosing liver diseases in both humans and animals. The indicator can serve as a diagnostic indicator for assessing the extent of liver cell damage and as a marker for chronic liver diseases. The level of kallistatin decreases significantly in cirrhosis and is directly related to the biochemical indices of blood. Furthermore, the lower the level of kallistatin, the more pronounced the degree of liver cell damage. However, this indicator has not been sufficiently investigated in laboratory diagnosis, particularly its relationship to liver disease. Further research is needed to elucidate its diagnostic potential and clinical significance in liver pathology. In addition, for animals with chronic liver disease, it has been found that kallistatin can serve as a useful and reliable diagnostic indicator of liver health, particularly in cases of cirrhosis.