Tip110 Expression Facilitates the Release of HEXIM1 and pTEFb from the 7SK Ribonucleoprotein Complex Involving Regulation of the Intracellular Redox Level-Reference-Cited by-同舟云学术

Tip110 Expression Facilitates the Release of HEXIM1 and pTEFb from the 7SK Ribonucleoprotein Complex Involving Regulation of the Intracellular Redox Level

Published:2021 Issue:8 Volume:12 Page:2113
ISSN:2152-5250
Container-title:Aging and disease
language:en
Short-container-title:Aging and disease

Author:

Liu Ying,Li Lu,Timani Khalid,White Carl,He Johnny J

Publisher

Aging and Disease

Subject

Cell Biology,Neurology (clinical),Geriatrics and Gerontology,Pathology and Forensic Medicine

Link

http://www.aginganddisease.org/fileup/2152-5250/PDF/ad-0-0-0-2105301610-1.pdf

Reference60 articles.

1. Li Qintong, Price Jason P, Byers Sarah A, et al. (2005). Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186. J Biol Chem, 280:28819-26.

2. Chen Ruichuan, Yang Zhiyuan, Zhou Qiang (2004). Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. J Biol Chem, 279:4153-60.

3. Lu X, Zhu X, Li Y, et al. (2016). Multiple P-TEFbs cooperatively regulate the release of promoter-proximally paused RNA polymerase II. Nucleic acids research, 44:6853-67.

4. Peterlin BM, Brogie JE, Price DH (2012). 7SK snRNA: A noncoding RNA that plays a major role in regulating eukaryotic transcription. Wiley interdisciplinary reviews. RNA, 3:92-103.

5. Dong Kun Lee, Hai Ou Duan, Chawnshang Chang (2001). Androgen receptor interacts with the positive elongation factor P-TEFb and enhances the efficiency of transcriptional elongation. J Biol Chem, 276:9978-84.

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