Localization of Alkaline Phosphatase and Proteins Related to Intercellular Junctions in Rat Hepatoma Cell Line McA-RH 7777-Reference-Cited by-同舟云学术

Localization of Alkaline Phosphatase and Proteins Related to Intercellular Junctions in Rat Hepatoma Cell Line McA-RH 7777

Published:2004-07 Issue:7 Volume:52 Page:979-983
ISSN:0022-1554
Container-title:Journal of Histochemistry & Cytochemistry
language:en
Short-container-title:J Histochem Cytochem.

Author:

Chida Kohsuke¹,Taguchi Meiko¹

Affiliation:

1. Department of Anatomy, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, Japan

Abstract

We investigated the localization of alkaline phosphatase (ALP) and three proteins related to intercellular junctions in the McA-RH 7777 rat hepatoma cell line to determine if the formation of junctions between adjacent McA-RH 7777 cells triggers translocation of ALP from cytoplasm to the plasma membrane. Contact between adjacent McA-RH 7777 cells promotes translocation of ALP from the Golgi area of the cytoplasm to the plasma membrane, and also promotes translocation of two proteins, E-cadherin and ZO-1, related to intercellular junctions, from cytoplasm to the plasma membrane. (J Histochem Cytochem 52:979–983, 2004)

Publisher

SAGE Publications

Subject

Histology,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1369/jhc.3B6220.2004

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