Comparison of standard T2-weighted turbo spin echo and volumetric interpolated breath-hold examination magnetic resonance imaging sequences in the assessment of articular process dysplasia in Pug dogs with thoracolumbar myelopathy

Abstract

IntroductionA retrospective study to compare the classification, as normal, hypoplastic or aplastic, of thoracic (T10-T13) caudal articular process (CAP) morphology in Pug dogs with a thoracolumbar myelopathy as normal, hypoplastic or aplastic, between T2 weighted Turbo Spin Echo (T2W-TSE), in sagittal and transverse planes, and Volumetric Interpolated Breath-hold Examination (VIBE) Magnetic Resonance Imaging (MRI) sequences, in comparison to Computed Tomography (CT). We hypothesized a stronger agreement for VIBE in comparison to T2W-TSE.ResultsDiagnostic accuracy of T2W-TSE was inferior to VIBE for aplastic (60%, 95% CI 0.561–0.639 vs. 78%, 95%CI 0.744–0.815) hypoplastic (44%, 95%CI 0.427–0.452 vs. 62.5%, 95%CI 0.595–0.655) and normal CAP (70%, 95%CI 0.655–0.744 vs. 87%, 95%CI 0.848–0.892). Superior accuracy of classification using VIBE vs. T2W-TSE sequences using the McNemar Chi squared test was significant for aplastic (p = 0.0002) and normal CAP (p = 0.004). VIBE sequences had a sensitivity of 96% and specificity of 75% to detect CAP abnormality and with T2W-TSE imaging sensitivity 81% and specificity of 75%.DiscussionThree-dimensionally reconstructable VIBE sequences were significantly more accurate than traditional T2W-TSE MRI sequences in classifying CAP morphology, which should reduce the need for CT for pre-operative assessment.