Author:
Wijesuriya Nadeev,Elliott Mark K.,Mehta Vishal,De Vere Felicity,Strocchi Marina,Behar Jonathan M.,Niederer Steven A.,Rinaldi Christopher A.
Abstract
Non-responders to Cardiac Resynchronization Therapy (CRT) represent a high-risk, and difficult to treat population of heart failure patients. Studies have shown that these patients have a lower quality of life and reduced life expectancy compared to those who respond to CRT. Whilst the first-line treatment for dyssynchronous heart failure is “conventional” biventricular epicardial CRT, a range of novel pacing interventions have emerged as potential alternatives. This has raised the question whether these new treatments may be useful as a second-line pacing intervention for treating non-responders, or indeed, whether some patients may benefit from these as a first-line option. In this review, we will examine the current evidence for four pacing interventions in the context of treatment of conventional CRT non-responders: CRT optimization; multisite left ventricular pacing; left ventricular endocardial pacing and conduction system pacing.
Subject
Physiology (medical),Physiology
Cited by
1 articles.
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1. Cardiac Contractility Modulation for Heart Failure: Current and Future Directions;Journal of the Society for Cardiovascular Angiography & Interventions;2023-11