Optimizing Aggregated N-Of-1 Trial Designs for Predictive Biomarker Validation: Statistical Methods and Theoretical Findings

Author:

Hendrickson Rebecca C.,Thomas Ronald G.,Schork Nicholas J.,Raskind Murray A.

Funder

National Institutes of Health

Publisher

Frontiers Media SA

Reference45 articles.

1. The DEcIDE Methods Center N-of-1 Guidance Panel Duan N, Eslick I. Introduction to N-of-1 trials: indications and barriers;Kravitsz,2014

2. Personalized medicine: time for one-person trials;Schork;Nature.,2015

3. The DEcIDE Methods Center N-of-1 Guidance Panel Duan N, Eslick I. An ethical framework for N-of-1 trials: clinical care, quality improvement or human subjects research?;Punja,2014

4. Trial of prazosin for post-traumatic stress disorder in military veterans;Raskind;N Engl J Med.,2018

5. The DEcIDE Methods Center N-of-1 Guidance Panel (Duan N EI. Statistical design and analytic considerations for N-of-1 trials;Schmid,2014

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