Author:
Yeung Cindy Hoi Ting,Verstegen Ruud H. J.,Greenberg Rachel,Lewis Tamorah Rae
Abstract
Core clinical pharmacology principles must be considered when designing and executing neonatal clinical trials. In this review, the authors discuss important aspects of drug dose selection, pharmacokinetics, pharmacogenetics and pharmacodynamics that stakeholders may consider when undertaking a neonatal or infant clinical trial.
Subject
Pediatrics, Perinatology and Child Health