In vitro and in vivo Human Metabolism of (S)-[18F]Fluspidine – A Radioligand for Imaging σ1 Receptors With Positron Emission Tomography (PET)-Reference-Cited by-同舟云学术

In vitro and in vivo Human Metabolism of (S)-[18F]Fluspidine – A Radioligand for Imaging σ1 Receptors With Positron Emission Tomography (PET)

Published:2019-06-13 Issue: Volume:10 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Ludwig Friedrich-Alexander,Fischer Steffen,Houska Richard,Hoepping Alexander,Deuther-Conrad Winnie,Schepmann Dirk,Patt Marianne,Meyer Philipp M.,Hesse Swen,Becker Georg-Alexander,Zientek Franziska Ruth,Steinbach Jörg,Wünsch Bernhard,Sabri Osama,Brust Peter

Funder

Deutsche Forschungsgemeinschaft

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference40 articles.

1. Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28.;Amini;Anal. Bioanal. Chem.,2013

2. Role of human liver microsomes in in vitro metabolism of drugs-a review.;Asha;Appl. Biochem. Biotechnol.,2010

3. The role of positron emission tomography imaging in understanding Alzheimer’s disease.;Barthel;Expert Rev. Neurother.,2015

4. PET imaging evaluation of four σ1 radiotracers in nonhuman primates.;Baum;J. Nucl. Med.,2017

5. Metabolism of the A1 adenosine receptor positron emission tomography ligand [18F]8-cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine ([18F]CPFPX) in rodents and humans.;Bier;Drug Metab. Disp.,2006

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current status of PET tracers for the early diagnosis of Alzheimer's disease;TrAC Trends in Analytical Chemistry;2024-03

2. [18F]Fluspidine—A PET Tracer for Imaging of σ1 Receptors in the Central Nervous System;Pharmaceuticals;2024-01-28

3. Design and Biological Evaluation of Small-Molecule PET-Tracers for Imaging of Programmed Death Ligand 1;Cancers;2023-05-06

4. A Pharmacokinetic and Metabolism Study of the TRPC6 Inhibitor SH045 in Mice by LC-MS/MS;International Journal of Molecular Sciences;2022-03-26

5. Recent in vivo advances of spirocyclic scaffolds for drug discovery;Expert Opinion on Drug Discovery;2022-03-25