Author:
Chen Rong,Tang Ling-hua,Sun Tao,Zeng Zi,Zhang Yun-yan,Ding Ke,Meng Qing-tao
Abstract
Fentanyl-induced cough (FIC) often occurs after intravenous bolus administration of fentanyl analogs during induction of general anesthesia and analgesia procedure. The cough is generally benign, but sometimes it causes undesirable side effects, including elevated intra-abdominal, intracranial or intraocular pressure. Therefore, understanding the related mechanisms and influencing factors are of great significance to prevent and treat the cough. This paper reviews the molecular mechanism, influencing factors and preventive administration of FIC, focusing on the efficacy and side effects of various drugs in inhibiting FIC to provide some medical reference for anesthesiologists.
Subject
Pharmacology (medical),Pharmacology
Reference97 articles.
1. Fentanyl attenuates the hemodynamic response to endotracheal intubation more than the response to laryngoscopy;Adachi;Anesth. Analg.,2002
2. Salbutamol, beclomethasone or sodium chromoglycate suppress coughing induced by iv fentanyl;Agarwal;Can. J. Anaesth.,2003
3. Comparison of the incidence and severity of cough induced by sufentanil and fentanyl: a prospective, randomised, double-blind study;Agarwal;Anaesthesia,2007
4. Pentazocine pretreatment suppresses fentanyl-induced cough;Ai;Pharmacol. Rep.,2010
5. A huffing manoeuvre, immediately before induction of anaesthesia, prevents fentanyl-induced coughing: a prospective, randomized, and controlled study;Ambesh;Br. J. Anaesth.,2010