Immune response treated with bone marrow mesenchymal stromal cells after stroke

Author:

Wang Zili,Wang Xudong,Liao Yidong,Chen Guangtang,Xu Kaya

Abstract

Stroke is a leading cause of death and long-term disability worldwide. Tissue plasminogen activator (tPA) is an effective treatment for ischemic stroke. However, only a small part of patients could benefit from it. Therefore, finding a new treatment is necessary. Bone marrow mesenchymal stromal cells (BMSCs) provide a novel strategy for stroke patients. Now, many patients take stem cells to treat stroke. However, the researches of the precise inflammatory mechanism of cell replacement treatment are still rare. In this review, we summarize the immune response of BMSCs treated to stroke and may provide a new perspective for stem cell therapy.

Funder

National Natural Science Foundation of China

Publisher

Frontiers Media SA

Subject

Neurology (clinical),Neurology

Reference76 articles.

1. Bypass surgery for ischemic stroke caused by intracranial artery stenosis or occlusion;Soufiany;Brain Sci Adv,2018

2. Stand alone or join forces?;Incontri Abraham,2019

3. Filling the gaps on stroke research: focus on inflammation and immunity;Levard;Brain Behav Immun.,2021

4. Role of damage associated molecular pattern molecules (DAMPs) in aneurysmal subarachnoid hemorrhage (aSAH);Chaudhry;Int J Mol Sci,2018

5. Role of DAMPs and of leukocytes infiltration in ischemic stroke: insights from animal models and translation to the human disease;Stanzione,2020

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Advances in neuroprotective therapy for acute ischemic stroke;Exploration of Neuroprotective Therapy;2024-02-27

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3