Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

Author:

Ilieva Kristina M.,Fazekas-Singer Judit,Achkova Daniela Y.,Dodev Tihomir S.,Mele Silvia,Crescioli Silvia,Bax Heather J.,Cheung Anthony,Karagiannis Panagiotis,Correa Isabel,Figini Mariangela,Marlow Rebecca,Josephs Debra H.,Beavil Andrew J.,Maher John,Spicer James F.,Jensen-Jarolim Erika,Tutt Andrew N.,Karagiannis Sophia N.

Funder

Breast Cancer Now

Cancer Research UK

Boehringer Ingelheim Fonds

Medical Research Council

Austrian Science Fund

Academy of Medical Sciences

National Institute for Health Research

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

Reference76 articles.

1. Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2;Cuello;Cancer Res,2001

2. Insights into HER2 signaling from step-by-step optimization of anti-HER2 antibodies;Fu;MAbs,2014

3. The HER2 receptor in breast cancer: pathophysiology, clinical use, and new advances in therapy;Mitri;Chemother Res Pract,2012

4. Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells;Molina;Cancer Res,2001

5. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer;Van Cutsem;N Engl J Med,2009

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