1. From the Robarts Research Institute, Department of Medical Biophysics, and Division of Respirology, Department of Medicine, Western University, 1151 Richmond St N, London, ON, Canada N6A 5B7 (G.P.); Centre for Heart Lung Innovation, St. Paul’s Hospital, Vancouver, Canada (R.L.E.); and Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, Canada (R.L.E.).