Oral Pyogenic Granuloma: A Narrative Review

Author:

Lomeli Martinez Sarah Monserrat1234ORCID,Carrillo Contreras Nadia Guadalupe3,Gómez Sandoval Juan Ramón35ORCID,Zepeda Nuño José Sergio6,Gomez Mireles Juan Carlos3,Varela Hernández Juan José1,Mercado-González Ana Esther7,Bayardo González Rubén Alberto8ORCID,Gutiérrez-Maldonado Adrián Fernando1ORCID

Affiliation:

1. Department of Medical and Life Sciences, University of Guadalajara (CUCiénega-UdeG), 1115 Ave. Universidad, Ocotlán 47810, Jalisco, Mexico

2. Master of Public Health, Department of Wellbeing and Sustainable Development, University of Guadalajara (CUNorte-UdeG), 23 Federal Highway, Km. 191, Colotlán 46200, Jalisco, Mexico

3. Periodontics Program, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico

4. Prostodontics Program, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico

5. Research Institute of Dentistry, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico

6. Microbiology and Pathology Department, Pathology Laboratory, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico

7. Antiguo Hospital Civil de Guadalajara “Fray Antonio Alcalde”, 777 Coronel Calderón, Guadalajara 44200, Jalisco, Mexico

8. Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico

Abstract

Pyogenic granuloma (PG) is a benign vascular lesion found predominantly in the oral cavity. Characterized by rapid growth and propensity to bleed, PG presents diagnostic challenges due to its similarity and alarming proliferation. This narrative review synthesizes current knowledge on the epidemiology, etiopathogenesis, clinical manifestations, and management of oral PG, with emphasis on recent advances in diagnostic and therapeutic approaches. The epidemiology of the injury is meticulously analyzed, revealing a higher incidence in women and a wide range of ages of onset. It delves into the etiopathogenesis, highlighting the uncertainty surrounding the exact causal factors, although historical attributions suggest an infectious origin. It exhaustively analyzes the clinical and histopathological aspects of oral PG, offering information on its various presentations and the importance of an accurate diagnosis to guide effective treatment. It details treatment strategies, emphasizing the personalized approach based on individual patient characteristics. This comprehensive review consolidates current knowledge on oral PG, highlighting the need for further research to clarify its pathogenesis and optimize treatment protocols.

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Reference123 articles.

1. Sarwal, P., and Lapumnuaypol, K. StatPearls, StatPearls Publishing.

2. Pyogenic granuloma of the gingiva: A misnomer?—A case report and review of literature;Gomes;J. Indian Soc. Periodontol.,2013

3. Oral pyogenic granuloma: Various concepts of etiopathogenesis;Kamal;J. Oral Maxillofac. Pathol.,2012

4. Heterogeneous conceptualization of etiopathogenesis: Oral pyogenic granuloma;Sharma;Natl. J. Maxillofac. Surg.,2019

5. Extragingival pyogenic granuloma associated with medication: Report of an unusual case;Ghalayani;Dent. Res. J.,2014

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