Varicocele: To Treat or Not to Treat?

Author:

Franco Antonio1,Proietti Flavia2ORCID,Palombi Veronica2,Savarese Gabriele2,Guidotti Michele3ORCID,Leonardo Costantino2,Ferro Fabio4,Manna Claudio5ORCID,Franco Giorgio2

Affiliation:

1. Department of Urology, Sant’Andrea Hospital, “Sapienza” University of Rome, 00185 Rome, Italy

2. Department of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, “Sapienza” University of Rome, 00185 Rome, Italy

3. Department of Urology, Nuovo Ospedale dei Castelli, 00040 Rome, Italy

4. Mater Dei Hospital, 00197 Rome, Italy

5. Biofertility IVF and Infertility Center, 00198 Rome, Italy

Abstract

Varicocele treatment in infertility still remains controversial. It is clear, in fact, that in many patients, varicocele has no impact on fertility. Recent scientific evidence demonstrated that varicocele treatment is beneficial in improving semen parameters and pregnancy rate when an appropriate selection of patients is made. The purpose of treating varicocele in adults is mainly to improve current fertility status. On the other hand, the goal of treatment in adolescents is to prevent testicular injury and maintain testicular function for future fertility. Hence, the key to the success of varicocele treatment seems to be a correct indication. The aim of this study is to review and summarize current evidence in managing varicocele treatment focusing on the controversies regarding surgical indications in adolescent and adult patients, and in other specific situations such as azoospermia, bilateral or subclinical varicocele, and prior to ART.

Publisher

MDPI AG

Subject

General Medicine

Reference83 articles.

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2. Epidemiology of Varicocele;Alsaikhan;Asian J. Androl.,2016

3. Varicocele Size and Results of Varicocelectomy in Selected Subfertile Men with Varicocele;Dubin;Fertil. Steril.,1970

4. Ultrasound Evaluation of Varicoceles: Guidelines and Recommendations of the European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for Detection, Classification, and Grading;Freeman;Eur. Radiol.,2020

5. (2023, May 15). WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Male. Available online: https://www.who.int/publications/i/item/9780521774741.

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